In this talk, I will give a broad overview of my research career as a lumper and a splitter. As a lumper I have made connections between power, gender, race, and social class; between superstitions, conspiracies, and illusory correlations; and between risky decisions and utilitarian choices. As a splitter, I have highlighted the distinctions between power and status, perspective-taking and empathy, stereotyping and prejudice, and shame and guilt. I will also present the DISCriminability Framework for understanding the conceptual distinctions between statistically correlated and theoretically connected variables. The DISCriminability Framework highlights a four-step process targeting Definitional distinctions, their Interactions, their discrete Sources, and their disparate Consequences. The DISCriminability Framework provides a roadmap for scholars to develop theoretically novel insights, for disciplines to achieve optimized parsimony, and for policymakers to generate new practical solutions and efficient treatments.